Proxy Materials 2022 Annual Meeting of Shareholders Tuesday, April 19, 2022 at 8:30 a.m. CT Cass Information Systems, Inc. 13001 Hollenberg Drive Bridgeton, Missouri 63044 2022 Proxy Supplement 2022 Proxy Statement 2021 10-K 2021 Proxy Statement 2020 10-K 2020 Proxy Statement 2019 10-K 2019 Proxy Statement 2018 10-K 2018 Proxy Statement 2017 10K 2017 Proxy Statement 2016 10K 2016 Proxy Statement 2015 10K 2014 10K 2015 Proxy Statement 2013 10K 2014 Proxy Statement 2012 10K 2013 Proxy Statement 2011 10K 2012 Proxy Statement 2010 10K 2011 Proxy Statement 2009 10K 2010 Proxy Statement 2008 10K 2009 Proxy Statement 2008 Proxy 10K 2007